Masane Amaha and her daughter Rihoko are fugitives running from government agents intent on separating them. After a betrayal leads to Rihoko’s kidnapping, Masane must confront a human-mimicking weapon designed for stealth kills. During the struggle, a burst of energy from Masane's wrist triggers a transformation into the Witchblade. This legendary power changes her physical form and attracts various rival organizations, all of whom seek to seize control of the artifact for their own ends.
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